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The Dragons host Lyon in the second round of European Challenge Cup action this afternoon at Rodney Parade.
The Men of Gwent faced French opposition in the first round last weekend, going down to a heavy defeat to Perpignan.
Head coach Filo Tiatia labelled the 41-17 result “unacceptable” and he will be looking for a response in Newport.
He has made 10 changes to that side, with Aaron Wainwright returning the headline act, while scrum-half Niall Armstrong makes his first start of the season at nine where he will be paired with Tinus De Beer at 10.
Wales duo Ben Carter and Rio Dyer remain rested.
The game, which kicks off at 3.15pm, is being broadcast on Premier Sports and there will also be live updates below.
Scroll down for updates
Dragons: O’Brien (capt); J Rosser, Richards, Owen, Anderson; De Beer, Armstrong; Kelleher-Griffiths, Burrows, Hunt, Douglas, Screech, Lewis-Hughes, Young, Wainwright.
Replacements: Austin, J Morris, James, Woodman, Keddie, Hope, Westwood, E Rosser.
Lyon: Dumortier; Diabou, Parisien, Balewairiki, Mathiron; Tchaptchet, Cassang; Rey, Sarragallet, Gomes Sa, Lambey (capt), Roux, Okuya, Shvangiradze, Gouzou.
Replacements: Marceline, Kaabeche, Maalo, Sanson, Botha, Baret, Gonzalez, Maraku.
Referee: Fillippo Russo (Italy)
Assistants: Lorenzo Pedezzi (Italy) & Riccardo Bonato (Italy)
TMO: Stefano Penne (Italy)
